Division of Host-Microbe Systems & Therapeutics
Center for Immunity, Infection & Inflammation
Printed cells of Pseudomonas fluorescens and Mucilaginibacter sp.
Our lab studies the complex interactions of microorganisms. Interactions between microbes, their environment, or their host are essential for global cycles and play a crucial role in health and disease. We deploy a community systems biology approach that involves both experimental and computational methods to unravel genome organization and community composition, metabolism, and exchanges microbes are engaged in. Furthermore, we predict outcomes to perturbation and design interventions strategies to selectively alter microbiomes.
This interdisciplinary approach engages lab members of diverse backgrounds in computational biology and mathematics, molecular biology and genetics, as well as physiology and microbiology.
Defining the intertwined crosstalk between different community members of the microbiome allows us to understand how complex systems are organized and maintained, to predict how these systems develop and react to changes, and to design targeted interventions to improve environments, as well as plant and human health.
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